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Ancrod and Fibrin Formation: Perspectives on Mechanisms of Action

BACKGROUND AND PURPOSE: Ancrod, derived from Malayan pit viper venom, has been tested as ischemic stroke treatment in clinical trials with inconsistent results. We studied the actions of ancrod on fibrinolysis pathways in patient samples and endothelial cell culture systems. METHODS: We analyzed fib...

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Detalhes bibliográficos
Main Authors: Liu, Shuo, Marder, Victor J., Levy, David E., Wang, Shur-Jen, Yang, Fan, Paganini-Hill, Annlia, Fisher, Mark J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236789/
https://ncbi.nlm.nih.gov/pubmed/21868728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.111.622753
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