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Mechanism of ancrod anticoagulation: A direct proteolytic effect on fibrin

Fibrin formed in response to ancrod, reptilase, or thrombin was reduced by β-mercaptoethanol and examined by sodium dodecyl sulfate polyacrylamide gel electrophoresis. It was found that ancrod progressively and totally digested the α-chains of fibrin monomers at sites different than plasmin; however...

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Detalhes bibliográficos
Main Authors: Pizzo, Salvatore V., Schwartz, Martin L., Hill, Robert L., McKee, Patrick A.
Formato: Artigo
Idioma:Inglês
Publicado em: 1972
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC292433/
https://ncbi.nlm.nih.gov/pubmed/4263497
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