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Tissue Plasminogen Activator Expression and Barrier Properties of Human Brain Microvascular Endothelial Cells

BACKGROUND: Tissue plasminogen activator (tPA) regulates fibrinolysis and is routinely used as ischemic stroke pharmacotherapy. We hypothesized that brain microvascular tPA expression and barrier properties of endothelial cells are substantially related. METHODS: Human brain microvascular endothelia...

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Detalhes bibliográficos
Publicado no:Cell Physiol Biochem
Main Authors: Yang, Fan, Liu, Shuo, Wang, Shur-Jen, Yu, Chuanhui, Paganini-Hill, Annlia, Fisher, Mark J.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7077105/
https://ncbi.nlm.nih.gov/pubmed/22178875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000335785
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