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PDE4 Regulates Tissue Plasminogen Activator Expression of Human Brain Microvascular Endothelial Cells
INTRODUCTION: Factors regulating brain tissue plasminogen activator (tPA) are pertinent for stroke. Recent observations have suggested a role for the phosphodiesterase-4 (PDE4) pathway in stroke pathogenesis, via an uncertain mechanism. We studied PDE4 regulation of tPA expression by human brain mic...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3359414/ https://ncbi.nlm.nih.gov/pubmed/22245243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2011.12.008 |
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