Dysfunctional TGF-β signaling with constitutively active Notch signaling in Barrett's esophageal adenocarcinoma

BACKGROUND: Esophageal adenocarcinoma is often considered to arise from a clonal stem like population of cells, potentially responsible for its poor prognosis. TGF-β and Notch signaling pathways play important roles in regulating self-renewal of stem cells, cell-fate determination. Both pathways are...

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Библиографические подробности
Главные авторы: Mendelson, Jonathan, Song, Shumei, Li, Ying, Maru, Dipen M, Mishra, Bibhuti, Davila, Marta, Hofstetter, Wayne L, Mishra, Lopa
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236645/
https://ncbi.nlm.nih.gov/pubmed/21305538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.25861
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