Notch Signaling Mediates Differentiation in Barrett’s Esophagus and Promotes Progression to Adenocarcinoma

BACKGROUND & AIMS: Studies are needed to determine the mechanism by which Barrett’s esophagus (BE) progresses to esophageal adenocarcinoma (EAC). Notch signaling maintains stem cells in the gastrointestinal tract and is dysregulated during carcinogenesis. We explored the relationship between Not...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Gastroenterology
Main Authors: Kunze, Bettina, Wein, Frederik, Fang, Hsin-Yu, Anand, Akanksha, Baumeister, Theresa, Strangmann, Julia, Gerland, Sophie, Ingermann, Jonas, Münch, Natasha Stephens, Wiethaler, Maria, Sahm, Vincenz, Sastre, Ana Hidalgo, Lange, Sebastian, Lightdale, Charles J, Bokhari, Aqiba, Falk, Gary W, Friedman, Richard A, Ginsberg, Gregory G, Iyer, Prasad G, Jin, Zhezhen, Nakagawa, Hiroshi, Shawber, Carrie J, Nguyen, TheAnh, Raab, William J., Dalerba, Piero, Rustgi, Anil K, Sepulveda, Antonia R, Wang, Kenneth K, Schmid, Roland M, Wang, Timothy C., Abrams, Julian A., Quante, Michael
פורמט: Artigo
שפה:Inglês
יצא לאור: 2020
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484392/
https://ncbi.nlm.nih.gov/pubmed/32325086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2020.04.033
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