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DNA Demethylation Dynamics

The discovery of cytosine hydroxymethylation (5hmC) suggested a simple means of demethylating DNA and activating genes. Further experiments, however, unearthed an unexpectedly complex process, entailing both passive and active mechanisms of DNA demethylation by the ten-eleven translocation (TET) and...

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Detalhes bibliográficos
Main Authors: Bhutani, Nidhi, Burns, David M., Blau, Helen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236603/
https://ncbi.nlm.nih.gov/pubmed/21925312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.08.042
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