DNA demethylation dynamics in the human prenatal germline

Global DNA demethylation in humans is a fundamental process that occurs in pre-implantation embryos and reversion to naïve ground state pluripotent stem cells (PSCs). However the extent of DNA methylation reprogramming in human germline cells is unknown. Here we performed whole-genome bisulfite sequ...

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發表在:Cell
Main Authors: Gkountela, Sofia, Zhang, Kelvin X, Shafiq, Tiasha A, Liao, Wen-wei, Hargan-Calvopiña, Joseph, Chen, Pao-Yang, Clark, Amander T
格式: Artigo
語言:Inglês
出版: 2015
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458157/
https://ncbi.nlm.nih.gov/pubmed/26004067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.05.012
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