IT-141, a Polymer Micelle Encapsulating SN-38, Induces Tumor Regression in Multiple Colorectal Cancer Models

Polymer micelles are promising drug delivery vehicles for the delivery of anticancer agents to tumors. Often, anticancer drugs display potent cytotoxic effects towards cancer cells but are too hydrophobic to be administered in the clinic as a free drug. To address this problem, a polymer micelle was...

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Bibliographische Detailangaben
Hauptverfasser: Carie, Adam, Rios-Doria, Jonathan, Costich, Tara, Burke, Brian, Slama, Richard, Skaff, Habib, Sill, Kevin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236496/
https://ncbi.nlm.nih.gov/pubmed/22187652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/869027
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