IT-141, a Polymer Micelle Encapsulating SN-38, Induces Tumor Regression in Multiple Colorectal Cancer Models

Polymer micelles are promising drug delivery vehicles for the delivery of anticancer agents to tumors. Often, anticancer drugs display potent cytotoxic effects towards cancer cells but are too hydrophobic to be administered in the clinic as a free drug. To address this problem, a polymer micelle was...

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Hlavní autoři: Carie, Adam, Rios-Doria, Jonathan, Costich, Tara, Burke, Brian, Slama, Richard, Skaff, Habib, Sill, Kevin
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2011
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236496/
https://ncbi.nlm.nih.gov/pubmed/22187652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/869027
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