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IT-141, a Polymer Micelle Encapsulating SN-38, Induces Tumor Regression in Multiple Colorectal Cancer Models

Polymer micelles are promising drug delivery vehicles for the delivery of anticancer agents to tumors. Often, anticancer drugs display potent cytotoxic effects towards cancer cells but are too hydrophobic to be administered in the clinic as a free drug. To address this problem, a polymer micelle was...

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Detalhes bibliográficos
Main Authors: Carie, Adam, Rios-Doria, Jonathan, Costich, Tara, Burke, Brian, Slama, Richard, Skaff, Habib, Sill, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236496/
https://ncbi.nlm.nih.gov/pubmed/22187652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/869027
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