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Environment-Sensitive Polymeric Micelles Encapsulating SN-38 Potently Suppress Growth of Neuroblastoma Cells Exhibiting Intrinsic and Acquired Drug Resistance
[Image: see text] Conventional treatment approaches fail to provide durable control over aggressive malignancies due to intrinsic or acquired drug resistance characteristic of high-risk disease. SN-38, a potent camptothecin analog specifically targeting DNA topoisomerase I cleavage complexes, has sh...
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| 發表在: | ACS Pharmacol Transl Sci |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American
Chemical Society
2020
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| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7887841/ https://ncbi.nlm.nih.gov/pubmed/33615176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.0c00182 |
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