Monoclonal antibody against epidermal growth factor receptor is internalized without stimulating receptor phosphorylation.

The down-regulation and internalization of the epidermal growth factor (EGF) receptors induced by two separate anti-EGF monoclonal antibodies (mAbs), IgG1 mAb-225 and -455, and by EGF was examined. mAb-225 competitively inhibits EGF binding and it is internalized to an extent comparable to EGF. The...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sunada, H, Magun, B E, Mendelsohn, J, MacLeod, C L
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1986
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC323616/
https://ncbi.nlm.nih.gov/pubmed/2424012
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak