Toward computer-aided site-directed mutagenesis of enzymes.
A preliminary attempt to simulate the observed effect of a site-directed mutagenesis of rat trypsin gives encouraging results. The calculations reproduce in a semiquantitative way the observed change in the activation barrier of the rate-limiting step of amide hydrolysis. This result, which did not...
Na minha lista:
| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1986
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323612/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3520555/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.11.3806 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|