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Kinetic analysis of the unique error signature of human DNA polymerase ν()
The fidelity of DNA synthesis by A-family DNA polymerases ranges from very accurate for bacterial, bacteriophage and mitochondrial family members to very low for certain eukaryotic homologues. The latter include Pol ν which, among all A-family polymerases, is uniquely prone to misincorporate dTTP op...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3235957/ https://ncbi.nlm.nih.gov/pubmed/22008035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201197p |
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