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Kinetic analysis of the unique error signature of human DNA polymerase ν()

The fidelity of DNA synthesis by A-family DNA polymerases ranges from very accurate for bacterial, bacteriophage and mitochondrial family members to very low for certain eukaryotic homologues. The latter include Pol ν which, among all A-family polymerases, is uniquely prone to misincorporate dTTP op...

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Autors principals: Arana, Mercedes E., Potapova, Olga, Kunkel, Thomas A., Joyce, Catherine M.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235957/
https://ncbi.nlm.nih.gov/pubmed/22008035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201197p
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