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A long-term siRNA strategy regulates fibronectin overexpression and improves vascular lesions in retinas of diabetic rats
PURPOSE: A sustained gene modulatory strategy is necessary for regulating abnormal gene expression in diabetic retinopathy, a long-term complication. We investigated the efficacy of a small interference RNA (siRNA) strategy in mediating the long-term downregulatory effect of fibronectin (FN) overexp...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Molecular Vision
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3235535/ https://ncbi.nlm.nih.gov/pubmed/22171163 |
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