A long-term siRNA strategy regulates fibronectin overexpression and improves vascular lesions in retinas of diabetic rats

PURPOSE: A sustained gene modulatory strategy is necessary for regulating abnormal gene expression in diabetic retinopathy, a long-term complication. We investigated the efficacy of a small interference RNA (siRNA) strategy in mediating the long-term downregulatory effect of fibronectin (FN) overexp...

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Hauptverfasser: Roy, Sumon, Nasser, Sigrid, Yee, Melissa, Graves, Dana T., Roy, Sayon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Molecular Vision 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235535/
https://ncbi.nlm.nih.gov/pubmed/22171163
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