Reduced Connexin 43 Expression and Its Effect on the Development of Vascular Lesions in Retinas of Diabetic Mice

PURPOSE. To examine whether diabetes-induced connexin 43 downregulation promotes retinal vascular lesions characteristic of diabetic retinopathy (DR). METHODS. Two animal models, streptozotocin-induced diabetic mice and Cx43 heterozygous knockout (Cx43(±)) mice, were studied to directly assess wheth...

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Autores principales: Bobbie, Michael W., Roy, Sumon, Trudeau, Kyle, Munger, Stephanie J., Simon, Alexander M., Roy, Sayon
Formato: Artigo
Lenguaje:Inglês
Publicado: Association for Research in Vision and Ophthalmology, Inc. 2010
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904019/
https://ncbi.nlm.nih.gov/pubmed/20130277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4489
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