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Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax

Intraluminal valves are required for the proper function of lymphatic collecting vessels and large lymphatic trunks like the thoracic duct. Despite recent progress in the study of lymphvasculogenesis and lymphangiogenesis, the molecular mechanisms controlling the morphogenesis of lymphatic valves re...

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Detalhes bibliográficos
Main Authors: Kanady, John D., Dellinger, Michael T., Munger, Stephanie J., Witte, Marlys H., Simon, Alexander M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134316/
https://ncbi.nlm.nih.gov/pubmed/21515254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.04.004
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