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Downregulation of Mitochondrial Connexin 43 by High Glucose Triggers Mitochondrial Shape Change and Cytochrome c Release in Retinal Endothelial Cells
PURPOSE. To determine connexin 43 (Cx43) localization in mitochondria and investigate the effects of high glucose (HG) on mitochondrial Cx43 (mtCx43) expression and whether altered mtCx43 channel activity is involved in promoting apoptosis in retinal endothelial cells. METHODS. MtCx43 localization w...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Association for Research in Vision and Ophthalmology
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3462478/ https://ncbi.nlm.nih.gov/pubmed/22915032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-9895 |
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