High Glucose–Induced Downregulation of Connexin 30.2 Promotes Retinal Vascular Lesions: Implications for Diabetic Retinopathy

PURPOSE. To investigate whether high glucose (HG) alters expression of connexin 30.2 (Cx30.2) and influences gap junction intercellular communication (GJIC) in retinal endothelial cells and promotes vascular lesions characteristic of diabetic retinopathy (DR). METHODS. Western blot analysis and immu...

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Main Authors: Manasson, Julia, Tien, Thomas, Moore, Colleen, Kumar, Nalin M., Roy, Sayon
Formato: Artigo
Idioma:Inglês
Publicado: The Association for Research in Vision and Ophthalmology 2013
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626527/
https://ncbi.nlm.nih.gov/pubmed/23385797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10815
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