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A New Strategy for the Synthesis of Chiral β-Alkynyl Esters via Sequential Palladium and Copper Catalysis

A new strategy for the synthesis of chiral β-alkynyl esters which relies on sequential Pd and Cu catalysis is reported. Terminal alkynes bearing aryl-, alkyl-, and silyl-groups can be employed without prior activation yielding a wide range of important chiral building blocks. The reaction sequence u...

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Détails bibliographiques
Auteurs principaux: Trost, Barry M., Taft, Benjamin R., Masters, James T., Lumb, Jean-Philip
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235047/
https://ncbi.nlm.nih.gov/pubmed/21557627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja203171x
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