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Asymmetric synthesis of chiral β-alkynyl carbonyl and sulfonyl derivatives via sequential palladium and copper catalysis

We present a full account detailing the development of a sequential catalysis strategy for the synthesis of chiral β-alkynyl carbonyl and sulfonyl derivatives. A palladium-catalyzed cross coupling of terminal alkyne donors with acetylenic ester, ketone, and sulfone acceptors generates stereodefined...

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Xehetasun bibliografikoak
Argitaratua izan da:Chem Sci
Egile Nagusiak: Trost, Barry M., Masters, James T., Taft, Benjamin R., Lumb, Jean-Philip
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Royal Society of Chemistry 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5044515/
https://ncbi.nlm.nih.gov/pubmed/27746892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc01724j
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