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Retrotransposon activation contributes to fragile X premutation rCGG-mediated neurodegeneration
Fragile X-associated tremor/ataxia syndrome (FXTAS) is a neurodegenerative disorder associated with fragile X premutation carriers. Previous studies have shown that fragile X rCGG repeats are sufficient to cause neurodegeneration and that the rCGG-repeat-binding proteins Pur α and heterogeneous nucl...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3235010/ https://ncbi.nlm.nih.gov/pubmed/21940752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr437 |
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