Loading...
Activation of mTOR Ameliorates Fragile X Premutation rCGG Repeat-Mediated Neurodegeneration
Fragile X associated tremor/ataxia syndrome (FXTAS) is a late onset neurodegenerative disorder caused by aberrant expansion of CGG repeats in 5′ UTR of FMR1 gene. The elevated mRNA confers a toxic gain-of-function thought to be the critical event of pathogenesis. Expressing rCGG(90) repeats of the h...
Na minha lista:
| Main Authors: | , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2013
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3633886/ https://ncbi.nlm.nih.gov/pubmed/23626835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062572 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|