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MicroRNA-277 Modulates the Neurodegeneration Caused by Fragile X Premutation rCGG Repeats

Fragile X-associated tremor/ataxia syndrome (FXTAS), a late-onset neurodegenerative disorder, has been recognized in older male fragile X premutation carriers and is uncoupled from fragile X syndrome. Using a Drosophila model of FXTAS, we previously showed that transcribed premutation repeats alone...

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Detalhes bibliográficos
Main Authors: Tan, Huiping, Poidevin, Mickael, Li, He, Chen, Dahua, Jin, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343002/
https://ncbi.nlm.nih.gov/pubmed/22570635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002681
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