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Correct End Use during End Joining of Multiple Chromosomal Double Strand Breaks Is Influenced by Repair Protein RAD50, DNA-dependent Protein Kinase DNA-PKcs, and Transcription Context

During repair of multiple chromosomal double strand breaks (DSBs), matching the correct DSB ends is essential to limit rearrangements. To investigate the maintenance of correct end use, we examined repair of two tandem noncohesive DSBs generated by endonuclease I-SceI and the 3′ nonprocessive exonuc...

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Bibliografische gegevens
Hoofdauteurs: Gunn, Amanda, Bennardo, Nicole, Cheng, Anita, Stark, Jeremy M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234933/
https://ncbi.nlm.nih.gov/pubmed/22027841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.309252
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