Dynamic Modulation of Prohormone Convertase 2 (PC2)-mediated Precursor Processing by 7B2 Protein: PREFERENTIAL EFFECT ON GLUCAGON SYNTHESIS

The small neuroendocrine protein 7B2 is required for the production of active prohormone convertase 2 (PC2), an enzyme involved in the synthesis of peptide hormones, such as glucagon and proopiomelanocortin-derived α-melanocyte-stimulating hormone. However, whether 7B2 can dynamically modulate pepti...

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Bibliographic Details
Main Authors: Helwig, Michael, Lee, Sang-Nam, Hwang, Jae Ryoung, Ozawa, Akihiko, Medrano, Juan F., Lindberg, Iris
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Protein Synthesis and Degradation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234932/
https://ncbi.nlm.nih.gov/pubmed/22013069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.281980
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