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Waixenicin A Inhibits Cell Proliferation through Magnesium-dependent Block of Transient Receptor Potential Melastatin 7 (TRPM7) Channels

Transient receptor potential melastatin 7 (TRPM7) channels represent the major magnesium-uptake mechanism in mammalian cells and are key regulators of cell growth and proliferation. They are expressed abundantly in a variety of human carcinoma cells controlling survival, growth, and migration. These...

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Hlavní autoři: Zierler, Susanna, Yao, Guangmin, Zhang, Zheng, Kuo, W. Cedric, Pörzgen, Peter, Penner, Reinhold, Horgen, F. David, Fleig, Andrea
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234757/
https://ncbi.nlm.nih.gov/pubmed/21926172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.264341
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