The Channel-Kinase TRPM7 as Novel Regulator of Immune System Homeostasis

por Nadolni, Wiebke, Zierler, Susanna
Publicado en Cells (2018)

Human Sensory Neuron-specific Mas-related G Protein-coupled Receptors-X1 Sensitize and Directly Activate Transient Receptor Potential Cation Channel V1 via Distinct Signaling Pathw...

por Solinski, Hans Jürgen, Zierler, Susanna, Gudermann, Thomas, Breit, Andreas
Publicado 2012

A single lysine in the N-terminal region of store-operated channels is critical for STIM1-mediated gating

por Lis, Annette, Zierler, Susanna, Peinelt, Christine, Fleig, Andrea, Penner, Reinhold
Publicado 2010

Editorial: TRP Channels in Inflammation and Immunity

por Partida-Sanchez, Santiago, Desai, Bimal N., Schwab, Albrecht, Zierler, Susanna
Publicado en Front Immunol (2021)

TRPM6 and TRPM7 differentially contribute to the relief of heteromeric TRPM6/7 channels from inhibition by cytosolic Mg(2+) and Mg·ATP

por Ferioli, Silvia, Zierler, Susanna, Zaißerer, Joanna, Schredelseker, Johann, Gudermann, Thomas, Chubanov, Vladimir
Publicado en Sci Rep (2017)

Waixenicin A Inhibits Cell Proliferation through Magnesium-dependent Block of Transient Receptor Potential Melastatin 7 (TRPM7) Channels

por Zierler, Susanna, Yao, Guangmin, Zhang, Zheng, Kuo, W. Cedric, Pörzgen, Peter, Penner, Reinhold, Horgen, F. David, Fleig, Andrea
Publicado 2011

TRPM7 kinase activity regulates murine mast cell degranulation

por Zierler, Susanna, Sumoza‐Toledo, Adriana, Suzuki, Sayuri, Dúill, Fionán Ó, Ryazanova, Lillia V., Penner, Reinhold, Ryazanov, Alexey G., Fleig, Andrea
Publicado en J Physiol (2016)

TRPM7 is essential for Mg(2+) homeostasis in mammals

por Ryazanova, Lillia V., Rondon, Lusliany J., Zierler, Susanna, Hu, Zhixian, Galli, Joanna, Yamaguchi, Terry P., Mazur, Andrzej, Fleig, Andrea, Ryazanov, Alexey G.
Publicado 2010

TRPM7 Kinase Is Essential for Neutrophil Recruitment and Function via Regulation of Akt/mTOR Signaling

por Nadolni, Wiebke, Immler, Roland, Hoelting, Kilian, Fraticelli, Marco, Ripphahn, Myriam, Rothmiller, Simone, Matsushita, Masayuki, Boekhoff, Ingrid, Gudermann, Thomas, Sperandio, Markus, Zierler, Susanna
Publicado en Front Immunol (2021)

NAADP and the two-pore channel protein 1 participate in the acrosome reaction in mammalian spermatozoa

por Arndt, Lilli, Castonguay, Jan, Arlt, Elisabeth, Meyer, Dorke, Hassan, Sami, Borth, Heike, Zierler, Susanna, Wennemuth, Gunther, Breit, Andreas, Biel, Martin, Wahl-Schott, Christian, Gudermann, Thomas, Klugbauer, Norbert, Boekhoff, Ingrid
Publicado 2014

TPC1 deficiency or blockade augments systemic anaphylaxis and mast cell activity

por Arlt, Elisabeth, Fraticelli, Marco, Tsvilovskyy, Volodymyr, Nadolni, Wiebke, Breit, Andreas, O’Neill, Thomas J., Resenberger, Stefanie, Wennemuth, Gunther, Wahl-Schott, Christian, Biel, Martin, Grimm, Christian, Freichel, Marc, Gudermann, Thomas, Klugbauer, Norbert, Boekhoff, Ingrid, Zierler, Susanna
Publicado en Proc Natl Acad Sci U S A (2020)

TRPM7 kinase activity is essential for T cell colonization and alloreactivity in the gut

por Romagnani, Andrea, Vettore, Valentina, Rezzonico-Jost, Tanja, Hampe, Sarah, Rottoli, Elsa, Nadolni, Wiebke, Perotti, Michela, Meier, Melanie A., Hermanns, Constanze, Geiger, Sheila, Wennemuth, Gunther, Recordati, Camilla, Matsushita, Masayuki, Muehlich, Susanne, Proietti, Michele, Chubanov, Vladimir, Gudermann, Thomas, Grassi, Fabio, Zierler, Susanna
Publicado en Nat Commun (2017)

Defects in TRPM7 channel function deregulate thrombopoiesis through altered cellular Mg(2+) homeostasis and cytoskeletal architecture

por Stritt, Simon, Nurden, Paquita, Favier, Remi, Favier, Marie, Ferioli, Silvia, Gotru, Sanjeev K., van Eeuwijk, Judith M M., Schulze, Harald, Nurden, Alan T., Lambert, Michele P., Turro, Ernest, Burger-Stritt, Stephanie, Matsushita, Masayuki, Mittermeier, Lorenz, Ballerini, Paola, Zierler, Susanna, Laffan, Michael A., Chubanov, Vladimir, Gudermann, Thomas, Nieswandt, Bernhard, Braun, Attila
Publicado en Nat Commun (2016)

Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function

por Gerndt, Susanne, Chen, Cheng-Chang, Chao, Yu-Kai, Yuan, Yu, Burgstaller, Sandra, Scotto Rosato, Anna, Krogsaeter, Einar, Urban, Nicole, Jacob, Katharina, Nguyen, Ong Nam Phuong, Miller, Meghan T, Keller, Marco, Vollmar, Angelika M, Gudermann, Thomas, Zierler, Susanna, Schredelseker, Johann, Schaefer, Michael, Biel, Martin, Malli, Roland, Wahl-Schott, Christian, Bracher, Franz, Patel, Sandip, Grimm, Christian
Publicado en eLife (2020)

Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival

por Chubanov, Vladimir, Ferioli, Silvia, Wisnowsky, Annika, Simmons, David G, Leitzinger, Christin, Einer, Claudia, Jonas, Wenke, Shymkiv, Yuriy, Bartsch, Harald, Braun, Attila, Akdogan, Banu, Mittermeier, Lorenz, Sytik, Ludmila, Torben, Friedrich, Jurinovic, Vindi, van der Vorst, Emiel PC, Weber, Christian, Yildirim, Önder A, Sotlar, Karl, Schürmann, Annette, Zierler, Susanna, Zischka, Hans, Ryazanov, Alexey G, Gudermann, Thomas
Publicado en eLife (2016)