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TRPM7 Channel Is Regulated by Magnesium Nucleotides via its Kinase Domain

TRPM7 is a Ca(2+)- and Mg(2+)-permeable cation channel that also contains a protein kinase domain. While there is general consensus that the channel is inhibited by free intracellular Mg(2+), the functional roles of intracellular levels of Mg·ATP and the kinase domain in regulating TRPM7 channel act...

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Hlavní autoři: Demeuse, Philippe, Penner, Reinhold, Fleig, Andrea
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151514/
https://ncbi.nlm.nih.gov/pubmed/16533898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200509410
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