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Receptor-mediated regulation of the TRPM7 channel through its endogenous protein kinase domain

TRPM7 is a ubiquitously expressed and constitutively active divalent cation-selective ion channel, whose basal activity is regulated by intracellular levels of Mg(2+) and Mg·ATP. We have investigated receptor-mediated mechanisms that may actively regulate TRPM7 activity. We here report that TRPM7 cu...

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Detalhes bibliográficos
Main Authors: Takezawa, Ryuichi, Schmitz, Carsten, Demeuse, Philippe, Scharenberg, Andrew M., Penner, Reinhold, Fleig, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC395914/
https://ncbi.nlm.nih.gov/pubmed/15069188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307565101
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