Selection and amplification of heterologous genes encoding adenosine deaminase in mammalian cells.

We demonstrate that an adenosine deaminase (ADA) cDNA gene can function as a dominant selectable and amplifiable marker for gene transfer experiments in mammalian cells. Cells that incorporate the gene can be selected by growth in the presence of low concentrations of the ADA inhibitor 2'-deoxy...

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Hlavní autoři: Kaufman, R J, Murtha, P, Ingolia, D E, Yeung, C Y, Kellems, R E
Médium: Artigo
Jazyk:Inglês
Vydáno: 1986
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC323467/
https://ncbi.nlm.nih.gov/pubmed/3486414
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