Sequencing of high-complexity DNA pools for identification of nucleotide and structural variants in regions associated with complex traits

We have used targeted genomic sequencing of high-complexity DNA pools based on long-range PCR and deep DNA sequencing by the SOLiD technology. The method was used for sequencing of 286 kb from four chromosomal regions with quantitative trait loci (QTL) influencing blood plasma lipid and uric acid le...

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Main Authors: Zaboli, Ghazal, Ameur, Adam, Igl, Wilmar, Johansson, Åsa, Hayward, Caroline, Vitart, Veronique, Campbell, Susan, Zgaga, Lina, Polasek, Ozren, Schmitz, Gerd, van Duijn, Cornelia, Oostra, Ben, Pramstaller, Peter, Hicks, Andrew, Meitinger, Tomas, Rudan, Igor, Wright, Alan, Wilson, James F, Campbell, Harry, Gyllensten, Ulf
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234506/
https://ncbi.nlm.nih.gov/pubmed/21811304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2011.138
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