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A Hepatocyte Growth Factor Receptor (Met)–Insulin Receptor hybrid governs hepatic glucose metabolism

Met is the transmembrane tyrosine kinase cell surface receptor for Hepatocyte Growth Factor (HGF) and is related to the insulin receptor (INSR) tyrosine kinase. Here we report that the HGF–Met axis controls metabolism by stimulating hepatic glucose uptake and suppressing hepatic glucose output. We s...

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Detalhes bibliográficos
Main Authors: Fafalios, Arlee, Ma, Jihong, Tan, Xinping, Stoops, John, Luo, Jianhua, DeFrances, Marie C., Zarnegar, Reza
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233634/
https://ncbi.nlm.nih.gov/pubmed/22081023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2531
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