A Hepatocyte Growth Factor Receptor (Met)–Insulin Receptor hybrid governs hepatic glucose metabolism

Met is the transmembrane tyrosine kinase cell surface receptor for Hepatocyte Growth Factor (HGF) and is related to the insulin receptor (INSR) tyrosine kinase. Here we report that the HGF–Met axis controls metabolism by stimulating hepatic glucose uptake and suppressing hepatic glucose output. We s...

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Main Authors: Fafalios, Arlee, Ma, Jihong, Tan, Xinping, Stoops, John, Luo, Jianhua, DeFrances, Marie C., Zarnegar, Reza
格式: Artigo
語言:Inglês
出版: 2011
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233634/
https://ncbi.nlm.nih.gov/pubmed/22081023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2531
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