A Hepatocyte Growth Factor Receptor (Met)–Insulin Receptor hybrid governs hepatic glucose metabolism

Met is the transmembrane tyrosine kinase cell surface receptor for Hepatocyte Growth Factor (HGF) and is related to the insulin receptor (INSR) tyrosine kinase. Here we report that the HGF–Met axis controls metabolism by stimulating hepatic glucose uptake and suppressing hepatic glucose output. We s...

Full description

Saved in:
Bibliographic Details
Main Authors: Fafalios, Arlee, Ma, Jihong, Tan, Xinping, Stoops, John, Luo, Jianhua, DeFrances, Marie C., Zarnegar, Reza
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233634/
https://ncbi.nlm.nih.gov/pubmed/22081023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2531
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items