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Genomic Instability Causes HGF Gene Activation in Colon Cancer Cells, Promoting Their Resistance to Necroptosis

BACKGROUND & AIMS: Genomic instability promotes colon carcinogenesis by inducing genetic mutations, but not all genes affected by this process have been identified. We investigated whether genomic instability in human colorectal cancer (CRC) cells produces mutations in the hepatocyte growth fact...

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Detalhes bibliográficos
Publicado no:Gastroenterology
Main Authors: Seneviratne, Danushka, Ma, Jihong, Tan, Xinping, Kwon, Yong-Kook, Muhammad, Eman, Melhem, Mona, DeFrances, Marie C., Zarnegar, Reza
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274190/
https://ncbi.nlm.nih.gov/pubmed/25244939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2014.09.019
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