Genomic Instability Causes HGF Gene Activation in Colon Cancer Cells, Promoting Their Resistance to Necroptosis

BACKGROUND & AIMS: Genomic instability promotes colon carcinogenesis by inducing genetic mutations, but not all genes affected by this process have been identified. We investigated whether genomic instability in human colorectal cancer (CRC) cells produces mutations in the hepatocyte growth fact...

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Publicat a:Gastroenterology
Autors principals: Seneviratne, Danushka, Ma, Jihong, Tan, Xinping, Kwon, Yong-Kook, Muhammad, Eman, Melhem, Mona, DeFrances, Marie C., Zarnegar, Reza
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274190/
https://ncbi.nlm.nih.gov/pubmed/25244939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2014.09.019
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