Purification, ultrastructure, and chemical analysis of Alzheimer disease amyloid plaque core protein.

Isolation of Alzheimer disease amyloid plaque core protein (APCP) was carried out by repetitive NaDodSO4/EDTA/sucrose extractions and by Ficoll-400 density-gradient centrifugations. The enriched APCP-Ficoll interface was labeled with the fluorochrome thioflavin T and separated from the contaminating...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Roher, A, Wolfe, D, Palutke, M, KuKuruga, D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1986
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323359/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3458224/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.8.2662
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