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Purification, ultrastructure, and chemical analysis of Alzheimer disease amyloid plaque core protein.

Isolation of Alzheimer disease amyloid plaque core protein (APCP) was carried out by repetitive NaDodSO4/EDTA/sucrose extractions and by Ficoll-400 density-gradient centrifugations. The enriched APCP-Ficoll interface was labeled with the fluorochrome thioflavin T and separated from the contaminating...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Roher, A, Wolfe, D, Palutke, M, KuKuruga, D
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323359/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3458224/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.8.2662
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