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Pazopanib, A Multitargeted Tyrosine Kinase Inhibitor, Reduces Diabetic Retinal Vascular Leukostasis and Leakage
OBJECTIVE: To determine the efficacy of pazopanib eye drops in the streptozotocin induced diabetic retinopathy rat model. METHODS: A 0.5 % w/v pazopanib suspension was prepared in phosphate buffered saline (PBS, pH 7.4) in the presence of 0.5 % w/v sodium carboxymethyl cellulose. Brown Norway rats w...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3233473/ https://ncbi.nlm.nih.gov/pubmed/21945644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mvr.2011.09.001 |
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