Nanoparticle-Mediated Expression of an Angiogenic Inhibitor Ameliorates Ischemia-Induced Retinal Neovascularization and Diabetes-Induced Retinal Vascular Leakage

OBJECTIVE: The aim of the study is to evaluate the effect of nanoparticle-mediated gene delivery of angiogenic inhibitors on retinal inflammation, vascular leakage, and neovascularization in diabetic retinopathy. RESEARCH DESIGN AND METHODS: An expression plasmid of plasminogen kringle 5 (K5), a nat...

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Bibliographische Detailangaben
Hauptverfasser: Park, Kyoungmin, Chen, Ying, Hu, Yang, Mayo, Aaron S., Kompella, Uday B., Longeras, Richard, Ma, Jian-xing
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2009
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712783/
https://ncbi.nlm.nih.gov/pubmed/19491211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-1327
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