The landscape of tyrosine kinase inhibitors in sarcomas: looking beyond pazopanib

Introduction: Tyrosine kinases are key mediators of intracellular signaling cascades and aberrations in these proteins have been implicated in driving oncogenesis through the dysregulation of fundamental cellular processes including proliferation, migration, and apoptosis. As such, targeting these p...

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Bibliografiske detaljer
Udgivet i:Expert Rev Anticancer Ther
Main Authors: Wilding, Christopher P, Elms, Mark L, Judson, Ian, Tan, Aik-Choon, Jones, Robin L, Huang, Paul H
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6882314/
https://ncbi.nlm.nih.gov/pubmed/31665941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14737140.2019.1686979
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