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The landscape of tyrosine kinase inhibitors in sarcomas: looking beyond pazopanib

Introduction: Tyrosine kinases are key mediators of intracellular signaling cascades and aberrations in these proteins have been implicated in driving oncogenesis through the dysregulation of fundamental cellular processes including proliferation, migration, and apoptosis. As such, targeting these p...

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Detalhes bibliográficos
Publicado no:Expert Rev Anticancer Ther
Main Authors: Wilding, Christopher P, Elms, Mark L, Judson, Ian, Tan, Aik-Choon, Jones, Robin L, Huang, Paul H
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6882314/
https://ncbi.nlm.nih.gov/pubmed/31665941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14737140.2019.1686979
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