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Is there a critical period for mossy fiber sprouting in a mouse model of temporal lobe epilepsy?

PURPOSE: Dentate granule cell axon (mossy fiber) sprouting creates an aberrant positive-feedback circuit that might be epileptogenic. Presumably, mossy fiber sprouting is initiated by molecular signals, but it is unclear whether they are expressed transiently or persistently. If transient, there mig...

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Autores principales: Lew, Felicia H., Buckmaster, Paul S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233231/
https://ncbi.nlm.nih.gov/pubmed/22092282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2011.03315.x
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