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Rapamycin suppresses axon sprouting by somatostatin interneurons in a mouse model of temporal lobe epilepsy
PURPOSE: In temporal lobe epilepsy many somatostatin interneurons in the dentate gyrus die. However, some survive and sprout axon collaterals that form new synapses with granule cells. The functional consequences of GABAergic synaptic reorganization are unclear. Development of new methods to suppres...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3204172/ https://ncbi.nlm.nih.gov/pubmed/21883182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2011.03253.x |
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