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Prolonged Infusion of Inhibitors of Calcineurin or L-Type Calcium Channels Does Not Block Mossy Fiber Sprouting in a Model of Temporal Lobe Epilepsy

PURPOSE: It would be useful to selectively block granule cell axon (mossy fiber) sprouting to test its functional role in temporal lobe epileptogenesis. Targeting axonal growth cones may be an effective strategy to block mossy fiber sprouting. L-type calcium channels and calcineurin, a calcium-activ...

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Detalhes bibliográficos
Main Authors: Ingram, Elizabeth A., Toyoda, Izumi, Wen, Xiling, Buckmaster, Paul S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007596/
https://ncbi.nlm.nih.gov/pubmed/18616558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2008.01704.x
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