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Prolonged Infusion of Inhibitors of Calcineurin or L-Type Calcium Channels Does Not Block Mossy Fiber Sprouting in a Model of Temporal Lobe Epilepsy

PURPOSE: It would be useful to selectively block granule cell axon (mossy fiber) sprouting to test its functional role in temporal lobe epileptogenesis. Targeting axonal growth cones may be an effective strategy to block mossy fiber sprouting. L-type calcium channels and calcineurin, a calcium-activ...

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Autors principals: Ingram, Elizabeth A., Toyoda, Izumi, Wen, Xiling, Buckmaster, Paul S.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007596/
https://ncbi.nlm.nih.gov/pubmed/18616558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2008.01704.x
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