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Novel Yeast Bioassay for High-Throughput Screening of Matrix Metalloproteinase Inhibitors

Diverse malfunctions in the expression and regulation of matrix metalloproteinases (MMPs) are often the cause of severe human diseases, bringing the identification of specific MMP inhibitors into major focus, particularly in anticancer treatment. Here, we describe a novel bioassay based on recombina...

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Autors principals: Diehl, Bjoern, Hoffmann, Thorsten M., Mueller, Nina C., Burkhart, Jens L., Kazmaier, Uli, Schmitt, Manfred J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233093/
https://ncbi.nlm.nih.gov/pubmed/22003025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.06111-11
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