Novel Yeast Bioassay for High-Throughput Screening of Matrix Metalloproteinase Inhibitors

Diverse malfunctions in the expression and regulation of matrix metalloproteinases (MMPs) are often the cause of severe human diseases, bringing the identification of specific MMP inhibitors into major focus, particularly in anticancer treatment. Here, we describe a novel bioassay based on recombina...

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Main Authors: Diehl, Bjoern, Hoffmann, Thorsten M., Mueller, Nina C., Burkhart, Jens L., Kazmaier, Uli, Schmitt, Manfred J.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2011
主題:
Methods
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233093/
https://ncbi.nlm.nih.gov/pubmed/22003025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.06111-11
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