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Novel Yeast Bioassay for High-Throughput Screening of Matrix Metalloproteinase Inhibitors

Diverse malfunctions in the expression and regulation of matrix metalloproteinases (MMPs) are often the cause of severe human diseases, bringing the identification of specific MMP inhibitors into major focus, particularly in anticancer treatment. Here, we describe a novel bioassay based on recombina...

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Detalles Bibliográficos
Main Authors: Diehl, Bjoern, Hoffmann, Thorsten M., Mueller, Nina C., Burkhart, Jens L., Kazmaier, Uli, Schmitt, Manfred J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233093/
https://ncbi.nlm.nih.gov/pubmed/22003025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.06111-11
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