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A Critical Role of Mitochondrial Phosphatase Ptpmt1 in Embryogenesis Reveals a Mitochondrial Metabolic Stress-Induced Differentiation Checkpoint in Embryonic Stem Cells

Mitochondria are highly dynamic organelles that play multiple roles in cells. How mitochondria cooperatively modulate embryonic stem (ES) cell function during development is not fully understood. Global disruption of Ptpmt1, a mitochondrial Pten-like phosphatidylinositol phosphate (PIP) phosphatase,...

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Detaylı Bibliyografya
Asıl Yazarlar: Shen, Jinhua, Liu, Xia, Yu, Wen-Mei, Liu, Jie, Groot Nibbelink, Milou, Guo, Caiying, Finkel, Toren, Qu, Cheng-Kui
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233018/
https://ncbi.nlm.nih.gov/pubmed/21986498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05629-11
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